Tag: bacteriophage formulations

Emergence of multi-drug-resistant pathogens, as a result of huge application of antibiotics over a long time, is growing, and becoming increasingly difficult to treat. Bacteriophage technologies have therefore begun to garner great interest as alternatives to antibiotics. Rising prevalence of antimicrobial resistance and limited new antibiotic discoveries and development have sustained innovation and led to a renewal of interest in bacteriophages.

Advantages of phage therapy along with probiotics are gaining importance in the treatment of antibacterial-resistant infections, and demand is expected to grow over the next few years. Currently, players operating in the bacteriophage market are concentrating on meeting the needs of health professionals and patients by introducing novel phage therapies, and are investing in the development of advanced bacteriophage platforms.

As per Fact.MR’s analysis, the global bacteriophage market was valued at around US$ 39 Mn in 2019, and is projected to expand at a CAGR of over 4% through 2030.

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Bacteriophage Market Segmentation

By Region

• North America
• Europe
• East Asia
• South Asia
• Latin America
• Oceania
• Middle East & Africa

By Application

• Gastroenterology
• Respiratory Infection Treatment
• Skin Infection Treatment
• Wound Prophylaxis
• Urogenital Infection Treatment
• Others

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Essential Takeaways from the Bacteriophage Market Report

• Comparison of prominent players operating in the Bacteriophage Market.
• Recent developments and key strategies adopted by market players.
• Study of the micro and macro-economic growth indicators.
• Impact of the various factors on the value chain of the Bacteriophage Market.
• Growth opportunities for emerging market players in various regional markets.
• Current trends influencing the scenario of the Bacteriophage Market.

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Important queries related to the Bacteriophage Market addressed in the report:

1. Who are the most prominent players in the Bacteriophage Market?
2. What are the factors that are likely to hinder the growth of the Bacteriophage Market during the forecast period (2021-2031)?
3. Why is the concentration of tier-1 companies high in specific region?
4. How are the soaring prices of raw materials impacting the demand for keyword?
5. Why are market players eyeing opportunities in particular region?

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• One of the most established market research companies in India
• Round the clock customer support for clients across the globe
• Tailor-made reports available without additional costs
• Analysis of markets in over 150 countries
• Data collected from credible primary and secondary sources

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Award winning market research company Fact.MR has published the global bacteriophage market research report. According to the study, the market exhibits high growth potential, expected to yield credible gains through 2021. Long-term prospects also appear positive, with a predicted CAGR exceeding 4% through 2031.

The market was valued at approximately US$ 39 million in 2019, with surging applications in gastroenterology underpinning growth. A study conducted by the University of Gothenburg has established that nearly 40% of adults suffer from at least one functional gastrointestinal disorder, with disorders such as inflammatory bowel diseases being highly prevalent. Excessive reliance on antibiotics has led to a surge in antimicrobial resistance, causing numerous GI problems.

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According to the World Health Organization, the rate of resistance such as ciprofloxacin ranges between 8.4% and 92.9% for E. coli, and from 4.1% to 79.4% for K. Pneumoniae. Hence, the medical fraternity is investigating alternative treatment approaches, leading to heightened prospects for bacteriophage based supplements. Manufacturers are augmenting their research capacities, increasing the frequency of clinical trials and funding studies by establishing international level coalitions.

“Growing emphasis on maintaining gut microbiome health is prompting increased consumption of bacteriophage infused supplements and medicines. Recent government legislations such as the emergency investigational new drug (eIND) pathway by the US FDA have enabled healthcare settings to incorporate bacteriophage products in their diagnostics and treatment procedures,” remarks a Fact.MR analyst.

Key Takeaways from Fact.MR’s Bacteriophage Market Study

• By product, phage probiotics to enjoy an elevated market share, capturing over 9 out of 10 sales in 2021
• Gastroenterology to remain key bacteriophage therapeutics application area, owing to surging digestive tract disorders
• Oral bacteriophage products administration to remain highly preferred through 2021
• By distribution channel, retail and hospital pharmacies to emerge as the primary bacteriophage selling points
• US to experience high growth in bacteriophage sales, amid recent FDA approvals for the oral ingestion of bacteriophage cocktails in dietary supplements
• Increasing frequency of inhaled phage therapy to heighten growth prospects across the UK
• India, Russia & Georgia to emerge as lucrative bacteriophage markets amid accelerating research and development for determining efficacy of such products

Bacteriophage Market- Prominent Drivers

• The global bacteriophage market is driven by unceasing research & development activities for discovering novel treatment approaches
• Growing burden of antibiotic resistance is prompting patients to opt for safer alternatives, accelerating growth prospects
• Increasing global level coalitions amongst prominent manufacturers to accelerate bacteriophage development to stimulate further growth

Bacteriophage Market- Key Restraints

• Non-approval for human consumption by regulatory authorities due to perceived lacunae in effectiveness to restrain growth
• Uncertainties regarding potential mutations of bacteria strains leading to phage resistance development to limit commercial availability

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Competitive Landscape

Life Extension, Arthur Andrew Medical, Deerland Probiotics & Enzymes Inc., BioChimPharm, Micreos Human Health, Designs for Health, Accelerated Health Systems Inc., The Biostation, Probiotic America and Microgen are some prominent bacteriophage manufacturers included in Fact.MR’s report. Development of novel phase therapies to cater to specific healthcare requirements.

Life Extension, for instance, manufactures the FLORASSIST^® GI probiotic formula for ensuring the best digestive probiotic benefits. Being gluten free, non-GMO and vegetarian, the formula targets unwanted bacteria with a novel bacteriophage blend with various healthy probiotic strains.

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In 2019, BioChimPharm received a grant from the Georgian Innovation and Technology Agency for its PowerPhage veterinary antimicrobial. The product is highly effective in fighting harmful bacteria such as Salmonella, E. coli and Shigella, eliminating them without harming the beneficial microflora of the organism.

Key Questions Answered in the Report

• How is the bacteriophage market expected to assume shape in 2021?
• Why is Russia expected to emerge as a lucrative bacteriophage market?
• What drivers are expected to underpin future market outlook?
• Which restraints are expected to hamper the bacteriophages market growth?
• How are regulatory frameworks expected to influence market growth?
• Which are the prominent bacteriophage market players?

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Strategic Partnerships and Funding by Manufacturers for Development of Phage Therapeutics

Pharmaceutical companies are collaborating with a collective goal to foster innovation by working with biotech firms and companies, governments, and market stakeholders, to enable supportable investments into a novel pipeline of bacteriophage therapy.

For instance, Janssen Pharmaceuticals, Inc. and Locus Biosciences Inc., in 2019, signed a complete license and collaboration agreement to manufacture, develop, and commercialize CRISPR-Cas3-enhanced bacteriophage (crPhage) products for the treatment of various infections, such as respiratory tract infection caused by two key pathogens, and other related infections. For this, Locus will receive US$ 20 million as an initial payment, which is expected to reach US$ 798 million from future sales of the product.

Such partnerships between pharmaceutical companies are aimed at strengthening and accelerating phage therapy development to introduce new therapies by end of this decade.

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