Tag: BRAF-MEK

Categories
Pharmaceutical

BRAF-MEK Inhibitors Market Expansion To Be Persistent During 2022 – 2031

A BRAF-MEK inhibitors are a chemical or drug that restricts the mitogen-activated protein kinase and kinase, enzymes MEK1 and/or MEK2. The chemicals are used to affect the BRAF-MEK pathway which is often overactive in some cancers. Hence, the BRAF-MEK inhibitors have potential for treatment of some cancers, especially BRAF-mutated melanoma, and KRAS/BRAF mutated colorectal cancer. The demand for BRAF-MEK is likely to increase due to the increasing prevalence of cancer across the globe. This increase, along with a projected increase in branded therapy prescription, will boost the growth of the global BRAF-MEK market over the forecast period. Furthermore, the rising product approvals and launches of premium-priced metastatic therapies, will extend treatment duration and replace cheaper, generic, chemotherapy regimens will boost the global BRAF-MEK market growth.

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What are the Major Drivers Impacting Growth of the BRAF-MEK Inhibitors Market?

The ongoing clinical trials and studies on BRAF-MEK inhibitors as a new treatment option in the field of oncology is anticipated to drive the global BRAF-MEK inhibitors market during the forecast period. Researchers are actively involved in R&D activities on BRAF-MEK inhibitors to inflate its application to other invasive cancer indications, such as colorectal cancer due to the promising results of BRAF-MEK inhibitors in skin cancer. The inhibitors are under the phase 3 trial for the treatment of patients suffering from the malignant colorectal cancer. Furthermore, the increase in incidences of melanoma and rising awareness about new treatment options across the globe are contributing to the growth of the global BRAF-MEK inhibitors market. In 2018, according to the American Institute for Cancer Research 300,000 new cases of skin cancer were reported.

High target specificity and affinity is another factor, which is expected to drive growth of the global BRAF-MEK inhibitors market during the forecast period. Product approval is a major driver for the global MEK inhibitors market.

  • For Instance, In January 2019, Ono Pharmaceutical Co., Ltd. received manufacturing and marketing approval for MEKTOVI MEK inhibitors in Japan for the treatment of metastatic melanoma with BRAFV600 mutations

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How is the BRAF-MEK Inhibitors Creating Opportunities in the Field of Oncology?

The rising focus on BRAF-MEK inhibitors is likely to create a vast opportunity in the field of oncology. Development of BRAF-MEK inhibitors can serve as a new therapy to treat various malignancies. It is observed that BRAF-MEK can restrict the growth of tumor in people with malignant melanoma by disrupting the activity of MEK and BRAF kinases.

BRAF-MEK inhibitors is a selective inhibitor of the MAPK pathways. It targets a non-ATP site of the mitogen-activated protein kinases (MAP kinases). MAP kinases is a Serine/Threonine phosphorylating enzymes. MAP kinases is also known as extracellular signal-regulated kinases (ERKs). Aberrant signaling through the MAPK pathway can cause cancer.

How Rise in Investments in Cancer Research to Boost BRAF-MEK Inhibitors Market?

Medical research and healthcare are the major index of regional growth and development. Governments in several regions have shifted their funds toward unbounding new possibilities within medical research and healthcare system. Research for cancer has gained immense attention from regional authorities, due to this, the global BRAF-MEK inhibitors market is expected to become a goldmine of opportunities in the next coming years.

A well-known therapy, dual targeted therapy has been proven as a sound line of action for treating several types of diseases. Contemporary researches find that BRAF-MEK inhibitors could be used with BRAF inhibitors for treatment of metastatic melanoma. This research could lead market vendors to invest greater revenues in research and development activities.

 Key Segments of BRAF-MEK Inhibitors Market Covered in the Report

Based on drug, the global BRAF-MEK Inhibitors market has been segmented as

  • Trametinib
  • Cobimetinib
  • Binimetinib
  • Others

Based on distribution channel, the global BRAF-MEK Inhibitors market has been segmented as

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Based on the region, the global BRAF-MEK Inhibitors market has been segmented as

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East & Africa

Competitive Landscape

Key players such as

  • ONO PHARMACEUTICAL CO.LTD
  • AstraZeneca,
  • F. Hoffmann-La Roche Ltd
  • Novartis AG
  • Pfizer Inc.
  • Bristol-Myers Squibb,
  • BeiGene LTD
  • SpringWorks Therapeutics
  • Atriva Therapeutics GmbH
  • others are actively involved in offering BRAF-MEK inhibitors.

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What strategies are the Key Players adopting for Increasing their Market Share in the BRAF-MEK Inhibitors Market?

Major manufacturers of the global BRAF-MEK inhibitors have deep product penetration along with extensive distribution networks. Furthermore, the manufacturers of BRAF-MEK inhibitors are focusing on participating in international conferences and trade fairs to encourage their products and develop distribution partnerships and potential R&D collaborations.

Acquisitions, mergers, expansion, product branding, product launches, adoption of new technologies and strengthening of sales force are the key strategies adopted by manufacturers and integrators to increase the consumer base in different geographies

The companies operating in the global BRAF-MEK inhibitors market are also collaborating with research institutes and universities engaged in cancer research. This strategy could help vendors in understanding unmet needs and responding to them.

Why Retail Pharmacies Segment has Significant Growth Potential in BRAF-MEK Inhibitors Market?

The rising growth of the retail pharmacies segment is due to the increasing number of retail pharmacies across the world and easy availability of the BRAF-MEK inhibitors at the stores. Furthermore, the availability of BRAF-MEK inhibitors at specialty pharmacy stores and projected launch of new BRAF-MEK inhibitors during the forecast period are likely to propel the growth of the retail pharmacies segment in the global BRAF-MEK inhibitors market during the forecast period.

 What is the Repercussion of the Pandemic on the Growth of the BRAF-MEK Inhibitors Market?

COVID-19 pandemic has caused a disturbance in almost all the industries. Due to the outbreak, health care systems are negatively impacted, and delivery of medical facilities effectively to all patients has become a huge challenge worldwide. Covid-19 pandemic has changed the national healthcare priorities and spending but this is considered to be short-term impact on the chilblains treatment market. Due to global restrictions, the BRAF-MEK inhibitors market initially faced disturbance in the demand and supply, hence market is expected to experience a short-term negative growth.

The outbreak has brought on many aspects, like falling business assurance, uncertainty about future, massive slowing of the supply chain, and others. There has been a disruption in the supply of various API’s required in the production of oncology drugs, however, this is expected to be a temporary effect and the market is expected to recover soon. Furthermore, due to the coronavirus, the flow of patients into the hospitals and clinics have been reduced which has led to decline in the treatment rate.

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The Report Covers Exhaustive Analysis on:

  • BRAF-MEK Inhibitors Market Segments
  • BRAF-MEK Inhibitors Market Dynamics
  • Historical Actual Market Size, 2016 – 2020
  • BRAF-MEK Inhibitors Market Size & Forecast 2021 to 2031
  • Market Current Trends/Issues/Challenges
  • Competition & Companies involved
  • Market Drivers and Restraints

Regional Analysis Includes

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East & Africa

For More Insight- https://www.biospace.com/article/lab-automation-market-rising-demand-for-precision-based-diagnostics-and-medicine-delivery-driving-growth-fact-mr-study/

About Us:

Market research and consulting agency with a difference! That’s why 80% of Fortune 1,000 companies trust us for making their most critical decisions. While our experienced consultants employ the latest technologies to extract hard-to-find insights, we believe our USP is the trust clients have on our expertise. Spanning a wide range – from automotive & industry 4.0 to healthcare & retail, our coverage is expansive, but we ensure even the most niche categories are analyzed. Our sales offices in United States and Dublin, Ireland. Headquarter based in Dubai, UAE. Reach out to us with your goals, and we’ll be an able research partner.

Contact:

US Sales Office:
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Suite 400
Rockville, MD 20852
United States
Tel: +1 (628) 251-1583
Corporate Headquarter:
Unit No: AU-01-H Gold Tower (AU),
Plot No: JLT-PH1-I3A,
Jumeirah Lakes Towers,
Dubai, United Arab Emirates
Email: sales@factmr.com
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Categories
Pharmaceutical

Ongoing Studies on Novel Treatment and Clinical Trials Are Creating Growth Prospects for BRAF-MEK Inhibitors: Fact MR

As per a study by Fact.MR, the Global BRAF-MEK inhibitors market is expected to grow due to increasing prevalence of cancer such as melanoma, metastatic, and colorectal cancer.

According to the Centers for Disease Control and Prevention provided, around 77696 new cases of melanoma cancer were diagnosed every year from 2012 to 2016 in the U.S. alone.  Studies also suggest that men are more frequently affected by melanoma cancer than women. Rising incidence of melanoma cancer will fuel the demand for effective treatment, in turn creating growth opportunities for the market.

Approvals by regulatory bodies present in various countries are expected to propel the market growth. For instance, Roche announced the approval of Tecentriq, Cotellic, and Zelboraf for the treatment of BRAF V600 mutation-positive advanced melanoma patients in July 2020 by the U.S. Food and Drug Administration.

Request Brochure –https://www.factmr.com/connectus/sample?flag=B&rep_id=5662

Despite surging demand, the outbreak of the novel coronavirus has created disruption for the market across the globe. Product development and clinical trials have been severely affected. Nonetheless, the robust pipeline of BRAF-MEK inhibitor drugs is expected to significantly drive the growth of the market in the coming years.

Key Takeaways

  • The U.S. has emerged as a leading BRAF-MEK inhibitors market owing to the rise in numbers of product approvals by the regulatory authorities.
  • Rising incidence of NSCLC and melanomas is expected to drive the demand of BRAF-MEK inhibitors in the U.K.
  • In the Asia Pacific, key players of BRAF-MEK inhibitors have been investing increasingly in China and India due to a large patient base.
  • More than 4,000 patients are suffering from melanoma and around 700 deaths occur in Japan every year, as per a study by the Ministry of Health, Labor and Welfare of Japan. This will fuel the demand for BRAF-MEK inhibitor in the country.
  • Developing countries are investing in advanced healthcare and research & development driving the demand of BRAF-MEK inhibitors.

Enquire Before Buying – https://www.factmr.com/connectus/sample?flag=EB&rep_id=5662

Prominent Drivers

  • Increasing focus on early diagnosis of cancer is a key strend, positively affecting the market of BRAF-MEK inhibitors.
  • Global BRAF-MEK inhibitors market is soaring due to the increased spending on cancer research and drug development.
  • Several experts have joined hands for better research and development activities across the medical research brotherhood. This has been driving the market for BRAF-MEK inhibitors globally.

Key Restraints

  • Adverse effects of BRAF-MEK inhibitors, such as peripheral edema, diarrhea, and dermatitis acneiform is negatively affecting the demand of BRAF-MEK inhibitors.
  • Unfavorable reimbursement for approval for new melanoma therapies is hindering the growth of the market.
  • Extensive R&D activities and manufacturing makes the drugs very expensive, hampering the growth of the BRAF-MEK inhibitors market.

Competitive Landscape

Key players operating in the BRAF-MEK inhibitors market are SpringWorks Therapeutics, AstraZeneca, Pfizer Inc., ONO PHARMACEUTICAL CO.LTD, Novartis AG, BeiGene LTD, Atriva Therapeutics GmbH, F. Hoffmann-La Roche Ltd, and Bristol-Myers Squibb. The key players are focusing on participating in trade fairs and international conferences to encourage their distribution partnerships and potential R&D collaborations.

  • Array BioPharma Inc. and ONO PHARMACEUTICAL CO., LTD.  signed a license agreement to develop and commercialize MEKTOVI in the U.S., in May 2017
  • In January 2019, Ono Pharmaceutical Co., Ltd. received manufacturing and marketing approval for MEKTOVI MEK inhibitors for the treatment of metastatic melanoma with BRAFV600 mutations in Japan.

More Insights on the BRAF-MEK inhibitors market:

In its latest report, Fact.MR offers an unbiased analysis of the BRAF-MEK inhibitors market. In order to understand the global market potential, its growth, and scope, the market is segmented on the basis of drug (trametinib, cobimetinib, binimetinib, and others), distribution channel (hospital pharmacies, retail pharmacies, online pharmacies) across seven regions (North America, Latin America, Europe, South Asia, East Asia, Oceania and Middle East & Africa).

Explore Fact.MR’s Coverage on the Healthcare Domain:

At-Home Celiac Testing Market – According to the Latest Research by the Fact.MR The Celiac Testing market is set to gain growth in the forecast period 2021-2031 at a CAGR of 8.0%. The Reason for the growth is The increase in prevalence of Celiac disease globally.

Leukocyte Count Testing Market – According to the latest research by Fact.MR, the leukocyte count testing market is set to witness exponential growth with over 7%-8% CAGR during 2021-2031. Increasing bacterial infection with the growing adoption of point of care devices will witness a promising growth outlook for leukocyte count testing in the long run.

Polysaccharide Hemostatic System Market – According to the latest research by Fact.MR, Polysaccharide Hemostatic System market is set to witness upsurged growth during the year 2021-2031.

About Fact.MR

Market research and consulting agency with a difference! That’s why 80% of Fortune 1,000 companies trust us for making their most critical decisions. We have offices in US and Dublin, whereas our global headquarter is in Dubai. While our experienced consultants employ the latest technologies to extract hard-to-find insights, we believe our USP is the trust clients have on our expertise. Spanning a wide range – from automotive & industry 4.0 to healthcare & retail, our coverage is expansive, but we ensure even the most niche categories are analyzed. Reach out to us with your goals, and we’ll be an able research partner.

Contact:
US Sales Office:
11140 Rockville Pike
Suite 400
Rockville, MD 20852
United States
Tel: +1 (628) 251-1583
E-Mail: sales@factmr.com

Corporate Headquarter:
Unit No: AU-01-H Gold Tower (AU),
Plot No: JLT-PH1-I3A,
Jumeirah Lakes Towers,
Dubai, United Arab Emirates

Categories
Pharmaceutical

Ongoing Studies on Novel Treatment and Clinical Trials Are Creating Growth Prospects for BRAF-MEK Inhibitors: Fact MR

As per a study by Fact.MR, the Global BRAF-MEK inhibitors market is expected to grow due to increasing prevalence of cancer such as melanoma, metastatic, and colorectal cancer.

According to the Centers for Disease Control and Prevention provided, around 77696 new cases of melanoma cancer were diagnosed every year from 2012 to 2016 in the U.S. alone.  Studies also suggest that men are more frequently affected by melanoma cancer than women. Rising incidence of melanoma cancer will fuel the demand for effective treatment, in turn creating growth opportunities for the market.

Approvals by regulatory bodies present in various countries are expected to propel the market growth. For instance, Roche announced the approval of Tecentriq, Cotellic, and Zelboraf for the treatment of BRAF V600 mutation-positive advanced melanoma patients in July 2020 by the U.S. Food and Drug Administration.

Request Brochure –https://www.factmr.com/connectus/sample?flag=B&rep_id=5662

Despite surging demand, the outbreak of the novel coronavirus has created disruption for the market across the globe. Product development and clinical trials have been severely affected. Nonetheless, the robust pipeline of BRAF-MEK inhibitor drugs is expected to significantly drive the growth of the market in the coming years.

Key Takeaways

  • The U.S. has emerged as a leading BRAF-MEK inhibitors market owing to the rise in numbers of product approvals by the regulatory authorities.
  • Rising incidence of NSCLC and melanomas is expected to drive the demand of BRAF-MEK inhibitors in the U.K.
  • In the Asia Pacific, key players of BRAF-MEK inhibitors have been investing increasingly in China and India due to a large patient base.
  • More than 4,000 patients are suffering from melanoma and around 700 deaths occur in Japan every year, as per a study by the Ministry of Health, Labor and Welfare of Japan. This will fuel the demand for BRAF-MEK inhibitor in the country.
  • Developing countries are investing in advanced healthcare and research & development driving the demand of BRAF-MEK inhibitors.

Enquire Before Buying – https://www.factmr.com/connectus/sample?flag=EB&rep_id=5662

Prominent Drivers

  • Increasing focus on early diagnosis of cancer is a key strend, positively affecting the market of BRAF-MEK inhibitors.
  • Global BRAF-MEK inhibitors market is soaring due to the increased spending on cancer research and drug development.
  • Several experts have joined hands for better research and development activities across the medical research brotherhood. This has been driving the market for BRAF-MEK inhibitors globally.

Key Restraints

  • Adverse effects of BRAF-MEK inhibitors, such as peripheral edema, diarrhea, and dermatitis acneiform is negatively affecting the demand of BRAF-MEK inhibitors.
  • Unfavorable reimbursement for approval for new melanoma therapies is hindering the growth of the market.
  • Extensive R&D activities and manufacturing makes the drugs very expensive, hampering the growth of the BRAF-MEK inhibitors market.

Competitive Landscape

Key players operating in the BRAF-MEK inhibitors market are SpringWorks Therapeutics, AstraZeneca, Pfizer Inc., ONO PHARMACEUTICAL CO.LTD, Novartis AG, BeiGene LTD, Atriva Therapeutics GmbH, F. Hoffmann-La Roche Ltd, and Bristol-Myers Squibb. The key players are focusing on participating in trade fairs and international conferences to encourage their distribution partnerships and potential R&D collaborations.

  • Array BioPharma Inc. and ONO PHARMACEUTICAL CO., LTD.  signed a license agreement to develop and commercialize MEKTOVI in the U.S., in May 2017
  • In January 2019, Ono Pharmaceutical Co., Ltd. received manufacturing and marketing approval for MEKTOVI MEK inhibitors for the treatment of metastatic melanoma with BRAFV600 mutations in Japan.

More Insights on the BRAF-MEK inhibitors market:

In its latest report, Fact.MR offers an unbiased analysis of the BRAF-MEK inhibitors market. In order to understand the global market potential, its growth, and scope, the market is segmented on the basis of drug (trametinib, cobimetinib, binimetinib, and others), distribution channel (hospital pharmacies, retail pharmacies, online pharmacies) across seven regions (North America, Latin America, Europe, South Asia, East Asia, Oceania and Middle East & Africa).

Explore Fact.MR’s Coverage on the Healthcare Domain:

At-Home Celiac Testing Market – According to the Latest Research by the Fact.MR The Celiac Testing market is set to gain growth in the forecast period 2021-2031 at a CAGR of 8.0%. The Reason for the growth is The increase in prevalence of Celiac disease globally.

Leukocyte Count Testing Market – According to the latest research by Fact.MR, the leukocyte count testing market is set to witness exponential growth with over 7%-8% CAGR during 2021-2031. Increasing bacterial infection with the growing adoption of point of care devices will witness a promising growth outlook for leukocyte count testing in the long run.

Polysaccharide Hemostatic System Market – According to the latest research by Fact.MR, Polysaccharide Hemostatic System market is set to witness upsurged growth during the year 2021-2031.

About Fact.MR

Market research and consulting agency with a difference! That’s why 80% of Fortune 1,000 companies trust us for making their most critical decisions. We have offices in US and Dublin, whereas our global headquarter is in Dubai. While our experienced consultants employ the latest technologies to extract hard-to-find insights, we believe our USP is the trust clients have on our expertise. Spanning a wide range – from automotive & industry 4.0 to healthcare & retail, our coverage is expansive, but we ensure even the most niche categories are analyzed. Reach out to us with your goals, and we’ll be an able research partner.

Contact:
US Sales Office:
11140 Rockville Pike
Suite 400
Rockville, MD 20852
United States
Tel: +1 (628) 251-1583
E-Mail: sales@factmr.com

Corporate Headquarter:
Unit No: AU-01-H Gold Tower (AU),
Plot No: JLT-PH1-I3A,
Jumeirah Lakes Towers,
Dubai, United Arab Emirates